Here is a 20-year observational piece of research.
It confirms that T3 has no adverse effects on the heart and bones.
This disproves two of the major reasons that doctors use to avoid prescribing T3. The risk to the heart and to bone loss are the two most common reasons (excuses) used to avoid prescribing T3 to patients. It is common for me to hear from thyroid patients that their doctor does not want them on any T3 because it will cause a heart attack or heart issues. Thyroid patients are often also told that T3 will cause bone loss.
There is a minor reference in the report to psychological side effects of T3 only, but I believe that this is likely to be due to one of two factors:
1. Inept dosing of T3 – see the Recovering with T3 book for how to use T3 safely and effectively.
2. Other issues. Patients that eventually are given T3-monotherapy or T3-mostly therapy, often have other issues by this stage. See The Thyroid Patient’s Manual book, if you need more help with the exclusion or resolution of any of these other issues.
It is a very useful study and it throws out the argument that has been used in the past about T3 causing heart issues and bone loss, which many of us have known was not true anyway.
Here is the article:
“Safety review of liothyronine use: a 20-year observational follow-up study”
Enrique Soto-Pedre & Graham Leese
Endocrine Abstracts (2015) 38 OC5.6 | DOI: 10.1530/endoabs.38.OC5.6
http://www.endocrine-abstracts.org/ea/0038/ea0038OC5.6.htm
Best wishes,
Paul
(Updated in December 2022)
