Research Shows Successful Pregnancy of a Woman on T3-Only Thyroid Medication

This is a paper that supports everything I have ever written on the safe experience women have had throughout pregnancy when on T3-Only replacement therapy.

It is consistent with the information I provide in Chapter 18 (the T3 Treatment chapter) on page 147 of The Thyroid Patient’s Manual

Here it is:

“Normal neurodevelopment of children from a mother treated with only Liothyronine (T3) during pregnancy – a case report”
Sidrah Khan & Trevor Wheatley
Endocrine Abstracts (2016) 44 EP105
DOI: 10.1530/endoabs.44.EP105E

The woman concerned had very low FT4 during her pregnancy but there were no developmental issues with the foetus or baby.

This paper shows that T3 must indeed cross the placenta and provides the foetus with adequate thyroid hormone until after 20 weeks when it is self-sustaining.

It supports what I have been saying for many years about the misinformation and twisting of small pieces of research that often leads to people being frightened of T3-Only therapy.

There is no need to be frightened, as T3-Only therapy (if it is required) does replace the function of T4 without any adverse consequences. There is plenty of other anecdotal evidence of other women who have had successful pregnancies using T3-Only throughout the entire time from conception to birth. 

Dr. John C. Lowe also had many women patients who had successful pregnancies whilst on T3-Only.

Over the past ten years, there have been doctors and patients who have argued that only T4 can cross certain systems. The blood-brain barrier and central nervous system were being mentioned for a long time, as areas that only T4 could access. This has been shown to be totally false due to the discovery of active transporters:

I believe any other claims that T3 cannot replace the function of T4 will also be proven in time to be false. There is already enough evidence from people who live healthy lives over many years on T3-Only that I am certain of this.

As I mention on page 147 of The Thyroid Patient’s Manual, anyone who is still concerned about needing some T4 could take some during the first 20 weeks of pregnancy, after which the foetus is self-sustaining with its own thyroid hormones.

Best wishes,


Paul Robinson

Paul Robinson is a British author and thyroid patient advocate. The focus of his books and work is on helping patients recover from hypothyroidism. Paul has accumulated a wealth of knowledge on thyroid and adrenal dysfunction and their treatment. His three books cover all of this.

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